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COVID 19 and the Pandemic - Epidemiology

Lecture 8, from the MIT weekly lecture series

Excellent discussion for containing the pandemic through public health measures, including frequent testing with inexpensive antigen detection tools.

 

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OVEREVIEW: The Pandemic Is in Uncharted Territory

The United States set a new record for reported cases this week, breaking 500,000 for the first time in the pandemic as the third surge continued to build across nearly every state in the country.

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Remsdesvir: Some experts troubled about FDA approval for COVID-19 treatment

The United States reached a milestone, of sorts, when last week the Food and Drug Administration approved the first treatment for Covid-19.

The drug is called Veklury, although most people know it by its scientific name, remdesivir.

On Wednesday, its manufacturer, Gilead Sciences, said that remdesivir, which has been authorized for emergency use since the spring, had brought in $873 million in revenues so far this year and that it was the company’s second-best-selling drug in the third quarter, behind its H.I.V. drug, Biktarvy.

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New research shows that Covid-19 antibodies can neutralize the virus and last up to five months

There’s encouraging news about antibodies in a new paper published in the journal Science from researchers at New York City’s Mount Sinai Hospital. In their study of the antibody responses of patients with either mild or moderate Covid-19, antibody levels appeared to stay relatively stable for at least five months, and their presence was correlated with the inactivation of the virus.

Antibodies are molecules pumped out by the immune system in response to infection, and they have a role in preventing future infections, though exactly how they function within the context of Covid-19 isn’t clear yet. Scientists are urgently trying to figure out whether the presence of antibodies actually means a person is protected from future infection as well as how long antibodies last in the body. Knowing this is crucial, especially for vaccine development.

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Death Rates Have Dropped for Seriously Ill Covid Patients

The coronavirus struck the United States earlier this year with devastating force. In April, it killed more than 10,000 people in New York City. By early May, nearly 50,000 nursing home residents and their caregivers across the country had died.

But as the virus continued its rampage over the summer and fall, infecting nearly 8.5 million Americans, survival rates, even of seriously ill patients, appeared to be improving. At one New York hospital system where 30 percent of coronavirus patients died in March, the death rate had dropped to 3 percent by the end of June.

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